Pyrimidine Synthesis in Neurospora crassa: Gene-Enzyme Relationships
نویسندگان
چکیده
منابع مشابه
Tracer studies of pyrimidine synthesis by Neurospora crassa 1298.
Previous reports from thii laboratory have described the growth-supporting abilities of a-aminobutyric acid, propionic acid, and certain related compounds for the pyrimidmelessstrain, Neurospora crassu 1298 (1, 2). Tracer studies with aminobutyric acid-3-Cl4 indicated the use of this compound by the mold as a precursor of the pyrimidines of the ribonucleic acids (3). This conclusion, however, w...
متن کاملMetabolism of pyrimidine deoxyribonucleosides in Neurospora crassa.
The experiments in this report involve the following series of reactions which were previously demonstrated with purified enzyme preparations from Neurospora crassa: thymidine a yields thymine ribonucleoside b yields thymine c yields 5-hydroxymethyluracil d yields 5-formyluracil e yields uracil-5-carboxylic acid f yields uracil. The evidence for some of the reactions occurring in vivo has been ...
متن کاملMethionine synthesis in Neurospora crassa.
Horowitz and co-workers (Horowitz, 1947; Teas, Horowitz & Fling, 1948; Fling & Horowitz, 1951) have determined the pathway of methionine synthesis in Neurospora crassa, from genetic analysis of methionine-requiring mutant strains; it involves conversion of cysteine, via cystathionine, into homocysteine, which is methylated to methionine. A similar scheme has been suggested for methionine synthe...
متن کاملControl of trehalase synthesis in Neurospora crassa.
When an aconidial strain (STL6A) of Neurospora crassa is grown on carbon sources such as glucose, maltose, sucrose, etc., trehalase activity per unit weight of mycelium is very low. By contrast, media containing arabinose, glutamic acid, glycine, etc., which support growth only poorly, produce mycelium with very high trehalase activity. Retarding growth limiting the supply of a necessary nutrie...
متن کاملActivator-independent gene expression in Neurospora crassa.
A transgenic position effect that causes activator-independent gene expression has been described previously for three Neurospora crassa phosphate-repressible genes. We report analogous findings for two additional positively regulated genes, qa-2+ and ars-1+, indicating that such position effects are not limited to genes involved in phosphorus metabolism. In addition, we have characterized a nu...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1969
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.100.3.1371-1377.1969